WebBackground: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the response to rosuvastatin. Methods: FH … Web• Choose dosing for % LDL-C reduction: high-intensity statin (≥ 50%), moderateintensit- y statin (30– 49%). See Table 6-9 for statin “intensity” levels, effects, interactions, and contraindications. • Four main treatment benefit groups and their dosing intensity (Tables 5 and 6). Clinical ASCVD: If age ≤ 75 years, use high-intensity
2024 …
Web15 de dez. de 2024 · Patients age 40-75 without diabetes or CVD, but with LDL-C 70-189 and 10-year risk >7.5%, should consider a moderate-to-high intensity statin. + … WebHigh intensity dose is 4 times the moderate intensity dose. For patients with an LDL-C >100 mg/dL (2.6 mmol/L) and a greater than 10 percent risk of a CVD event within 10 years, … how to restore macbook to earlier date
A Comparison of Statin Therapies in Hypercholesterolemia in …
Web24 de mar. de 2024 · Objective To compare the efficacy of different statin treatments by intensity on levels of non-high density lipoprotein cholesterol (non-HDL-C) for the prevention of cardiovascular disease in people with diabetes. Design Systematic review and network meta-analysis. Data sources Medline, Cochrane Central Register of Controlled … Web31 de mai. de 2016 · Moderate- to high-intensity statin treatment is to be considered if 10-year risk ≥7.5% in those aged 40-75 years with LDL-C 70 to 189 mg/dL ... Table 1: Comparison of Guidelines Recommendations for Lipid Management Among Patients with CKD, on Dialysis, or Renal Transplant Recipients. Guideline. WebPatients with primary LDL-C levels of 190 mg per dL or greater. 3. Patients with diabetes mellitus, 40 to 75 years of age, with LDL-C levels of 70 to 189 mg per dL. 4. Patients without diabetes ... how to restore lost files in onedrive