WebFeb 16, 2016 · The current study was performed with the aim to evaluate the chaperoning ability, structural features, and aggregation propensity of wild-type and R12C mutant αB-crystallins (αB-Cry) under thermal stress and in the presence of calcium ion. The results of different spectroscopic analyses suggest that wild-type and mutant αB-Cry have … WebAug 11, 2009 · There are 2 α-crystallin genes, αA and αB, that encode for proteins that share ∼60% sequence identity ().In the eye lens, α-crystallins account for ≈40% of the total protein content ().The hetero-oligomeric mixtures of the 2 isoforms cannot be separated under native conditions ().Whereas αA-crystallin expression is mainly limited to the lens …
Structure of the crystallins Eye
WebCrystallins are the predominant structural proteins in the lens that are evolutionarily related to stress proteins. They were first discovered outside the vertebrate eye lens by Bhat and … WebMar 1, 2002 · In contrast to the orthologous protein found in other species, the C-terminal part differs and lacks the fourth beta/gamma crystallin 'Greek key' domain. Moreover, its non-specific tissue specificity suggests that it may have lost its function (PubMed:15853812). 1 publication chip gaines news
Crystallins in the eye: Function and pathology - PubMed
WebCrystal Trophy Singapore - Crystallin Marketing Manufactured from high quality crystal, the attractiveness of crystal trophies are enduring and perpetual. At Crystallin Marketing, we … WebApr 1, 2004 · Journal of Cell Science αB-Crystallin, one of the small heat-shock proteins, is constitutively expressed in various tissues including the lens of the eye. It has been suggested that αB-crystallin provides lens transparency but its function in nonlenticular tissues is unknown. granton bus