Biological applications of ionophores
WebJan 1, 2024 · Biological Applications of Ionophores. Article. Feb 1976; Berton C. Pressman; View. Effects of a low protein diet during pregnancy of the rhesus monkey. I. Reproductive efficiency. Article. WebIonophores are compounds that form lipid soluble, dynamically reversible complexes with cations and by this means facilitate specific ionic transport across biologic membranes (Pressman, 1976; Reed, 1982; Taylor et al., 1982 ). There are two major subclasses of ionophores, (1) neutral ionophores, which are highly toxic because they form charged ...
Biological applications of ionophores
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In chemistry, an ionophore (from Greek ion and -phore 'ion carrier') is a chemical species that reversibly binds ions. Many ionophores are lipid-soluble entities that transport ions across the cell membrane. Ionophores catalyze ion transport across hydrophobic membranes, such as liquid polymeric membranes (carrier-based ion selective electrodes) or lipid bilayers found in the living cells or synthetic vesicles (liposomes). Structurally, an ionophore contains a hydrophilic center … WebFeb 12, 2024 · Ion-selective electrodes (ISEs) are one of the most established types of chemical sensors, commercialized for a wide variety of applications ranging from their use as indicator electrodes in titrations to the direct determination of ions in clinical analysis. 1 This latter application has been largely aided by the implementation of ionophore-based …
WebApr 6, 2024 · Ionophores transport ions across biological membranes and have wide-ranging applications, but a platform for their rapid development does not exist. We report a platform for developing ionophores from metal-ion chelators, which are readily available with wide-ranging affinities and specificities, and structural data that can aid rational design. WebThe control of ion transport and homeostasis is a critical function of living organisms. In this perspective, an overview of different synthetic systems capable of facilitating the transmembrane transport of ions along with the biological activity exerted by these compounds is presented. Examples of both cat
WebAs it has turned out, medical and pharmaceutical applications of ionophores are limited, since the activity of ionophores is not restricted to microbial membranes. On the other … WebNov 1, 2024 · Cu ionophores include HQs that have a vast variety of biological applications. The most known compound of the HQ class is 7-iodo-5-chloro-8-hydroxyquinoline (CQ) that was first used as an ...
WebIonophores transport ions across biological membranes and have wide-ranging applications, but a platform for their rapid development does not exist. We report a platform for developing ionophores from metal-ion chelators, which are readily available with wide-ranging affinities and specificities, and structural data that can aid rational design.
WebMar 15, 2024 · As such, an essential part of all applications is a letter of sponsorship from the BSD faculty member with whom the applicant proposes to work, outlining the … birmingham stallions gearWebMar 4, 2024 · The development of new therapeutic agents should aim to increase selectivity and therefore reduce side effects. In addition, these agents should overcome cancer cell resistance and target cancer ... dangers of a hurricaneWebAnalogous ionophores have now been synthesized. Unique applications for these compounds are emerging, based either on their selective toxicity or ability to modify … birmingham stallions gameWebAs it has turned out, medical and pharmaceutical applications of ionophores are limited, since the activity of ionophores is not restricted to microbial membranes. On the other hand, ionophores were found to be wonderful tools in biochemical research at the cellular or membrane level. ... Pressman, B.C.: Biological applications of ionophores ... dangers of a high protein dietWebNov 1, 2024 · Copper ionophores alter the concentration, distribution, and reactivity of endogenous copper ions with consequent profound biological repercussions. The … birmingham stallions official websiteWebAug 13, 2024 · Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and … dangers of a hysterectomyWebBiological applications and evolutionary origins of ionophores. Pressman BC , deGuzman NT Adv Exp Med Biol, 84:285-300, 01 Jan 1977 Cited by: 6 articles PMID: … birmingham stallions football schedule 2022